A Case of Dermatomyositis Complicated with Pneumomediastinum Successfully treated with Cyclosporine A: a Case Report and Review of Literature.
10.4078/jrd.2014.21.6.317
- Author:
Joo Young CHUNG
1
;
Ha Yong YOON
;
Yun Jung CHOI
;
Soo Kyeong SONG
;
Won Seok LEE
;
Wan Hee YOO
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, Jeonju, Korea. ywhim@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Dermatomyositis;
Pneumomediastinum;
Interstitial lung disease;
Cyclosporin
- MeSH:
Cyclosporine*;
Dermatomyositis*;
Female;
Humans;
Lung Diseases, Interstitial;
Mediastinal Emphysema*;
Middle Aged;
Muscle, Skeletal;
Pulmonary Fibrosis
- From:Journal of Rheumatic Diseases
2014;21(6):317-321
- CountryRepublic of Korea
- Language:English
-
Abstract:
Dermatomyositis (DM) is a systemic inflammatory disease affecting skeletal muscles and other organs. Spontaneous pneumomediastinum (PnM) has been previously reported as a rare complication of DM and it is known to occur more frequently in patients with interstitial lung disease (ILD). Here we report on a case of a 52-year-old woman with DM who developed spontaneous PnM, which was treated successfully with high-dose steroid pulse therapy and cyclosporine A (CsA). This case suggests that CsA can be an effective therapeutic agent in DM refractory to glucocorticoid therapy, with ILD or pulmonary fibrosis accompanied by DM. CsA should be considered as an initial immunosuppressive agent for patients with PnM in DM.
