Hemorrhagic Cystitis with Giant Cells in Rheumatoid Arthritis Treating with Tacrolimus.
10.4078/jrd.2014.21.6.336
- Author:
In Suk MIN
1
;
YeonMi JU
;
Hyun young KIM
;
Yun Jung CHOI
;
Won Seok LEE
;
Wan Hee YOO
Author Information
1. Department of Rheumatology, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, Jeonju, Korea. ywhim@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Hemorrhagic cystitis;
Rheumatoid arthritis;
Tacrolimus
- MeSH:
Arthritis, Rheumatoid*;
Burns;
Cystitis*;
Drug Therapy;
Giant Cells*;
Hematuria;
Humans;
Inflammation;
Mucous Membrane;
Tacrolimus*;
Thrombocytopenia;
Urinary Bladder;
Urinary Bladder Neoplasms;
Urination
- From:Journal of Rheumatic Diseases
2014;21(6):336-339
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hemorrhagic cystitis is a diffuse inflammation of the mucosa of the bladder, characterized by hematuria and burning upon urination. This might be caused by a variety of reasons, including undergoing chemotherapy (such as cyclophosphamide), radiation therapy, bladder cancer, certain viruses, urinary infections, and thrombocytopenia. There are no previous reports of hemorrhagic cystitis associated with the use of tacrolimus. This is the first case of hemorrhagic cystitis due to tacrolimus for the treatment of rheumatoid arthritis. We describe a case of hemorrhagic cystitis with giant cells in a patient with rheumatoid arthritis treating with tacrolimus. Hematuria resolved spontaneously with discontinuation of the drug.
