Study on the Relationship Between MDR1 Gene Expression in Liver Cell and Cholesterol Calculus in Gallbladder
- VernacularTitle:肝细胞MDR1基因表达与胆囊胆固醇结石相关性研究
- Author:
Jun LIU
;
Houyong LONG
;
Hanxin MING
;
Chuanguo AN
;
Xun QU
- Publication Type:Journal Article
- Keywords:
Polymorase chain reaction MDR1 gene Cholesterol calculus in gallbladder
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the expression of MDR1 gene in liver cell and the formation of cholesterol calculus in gallbladder.Methods The mRNA expression level of MDR1 gene in liver cell of the cholesterol calculus group and the normal control group were measured through reverse transcriptionpolymerase chain reaction (RT-PCR), and microglobulin ?_2 was used as internal contrast.Results The MDR1 mRNA expression level of the cholesterol calculus group was lower than that of the normal control group(1.30?0.19 vs 2.25?(0.28), P
