The expression of uPA in gestational trophoblastic disease and the association with trophoblastic tumor invasiveness
- VernacularTitle:纤溶酶原激活剂在妊娠滋养细胞疾病中的表达及其与肿瘤侵袭的关系
- Author:
Xiu ZHENG
;
Guizhu WU
;
Zhongqing JIANG
- Publication Type:Journal Article
- Keywords:
urokinase-type plasminogen activator;
gestational trophoblastic disease;
in situ hybridization
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To study the expression of uPA in gestational trophoblastic cells and the relationship between uPA and the invasiveness of malignant trophoblastic tumor. Methods:73 samples from patients with gestational trophoblastic disease were harvested.In situ hybridization was employed to detect uPA expression in all of these samples. Results:① There was significant difference in the expression of uPA in cytotrophblasts among hydatidiform mole,invasive mole and choriocarcinoma(P
