Research on the correlation of Disabled-2 gene and tumors
- VernacularTitle:Disabled-2基因与肿瘤的相关研究
- Author:
Shuli SHAO
;
Yu CAI
- Publication Type:Journal Article
- Keywords:
Dab2 gene;
signal transduction;
tumor
- From:
China Oncology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Signal transduction is a very fine and complicated process that indudes participation in the cell propagation, division, maturation and apoptosis.Under normal circumstance disabled-2( Dab2) in human tissues participates in the signal transduction of the cell in order to allow the body to keep normal functions,but under some circumstances the absence of Dab2 influences the normal signal transduction path,leding to atypical cell changes.and the generation of tumors.This paper is a review on the construction and function of Dab2 and its related gene as well as the relation of Dab2 and tumors generation.