Case control study on etiological mechanism of autoimmune thyroid diseases
- VernacularTitle:自身免疫性甲状腺病的病因探讨
- Author:
Yi GONG
;
Bingyin SHI
;
Yan CUI
;
Yuan ZHAO
- Publication Type:Journal Article
- Keywords:
autoimmune thyroid disease;
etiology;
genetic factors;
environmental factors
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the relationship between autoimmune thyroid disease(AITD) and the genetic, immune and environmental factors. Methods A total of 500 patients with AITD and 206 healthy persons were included in this study. After carefully collecting the patient history and medical records, the inquiry forms were fulfilled to know about the genetic, immune and environmental factors. Statistical analysis was conducted using the SPSS statistical system. Results It was shown that family history of AITD, smoking and psychological factors were significantly different between AITD group and control(P0.05). Meanwhile, the difference of infection, contact with chemical poison, intake of sea food, miscarriage and blood type were also not significant between the patients and controls. Conclusion It is suggested that the heredity plays an important role in the pathogenesis of AITD. Smoking and psychological factors also have evident influence.
