Study on the function of the cryopreserved vascular endothelium
- VernacularTitle:程序化降温保存血管内皮功能的研究
- Author:
Yi LIU
;
Kesen XU
;
Kanji KAWACHI
;
Yuxin CHEN
- Publication Type:Journal Article
- Keywords:
Cryopreservation?Endothelium,vascular?Rats,Wistar
- From:
Chinese Journal of Current Advances in General Surgery
1999;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:We wanted to design an adequate method with which to cryopreserve rat aorta.Methods:Rat aorta were cryopreserved at 0.7℃/min,and kept frozen for 3 months.After being thawed,arteries were examined for contraction and vasodilation.Results:The mean contractions to KCL,PE,ET-1 and the relaxant ratio of SNP were better preserved in Group B than in Group C(P0.05).Conclusion:A modified cryopreservation technique can better preserves endothelial contractile function and endothelium independent vasodilation of the rat aorta than the conventional method,but the endothelium dependent vasodilation is badly preserved after the cryopreservation.
