Assessment of islet ?-cell function: from basic research to clinical practice
- VernacularTitle:胰岛?细胞功能评估——从基础到临床
- Author:
Weiping JIA
;
Kunsan XIANG
- Publication Type:Journal Article
- Keywords:
Islet ?-cells;
Functional assessment
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The deficiency in islet ?-cell secretion and (or) the decrease in insulin sensitivity of target tissue are the important pathophysiological mechanisms of diabetes. The methods for the assessment and evaluation of ?-cell function can be divided into: pulsatile insulin secretion, glucose secretagogues, non-glucose secretagogues (phase, peak value and duration) and other secretions. While the suitable method was chosen for the evaluation of ?-cell function, the sensitivity and specificity of different methods in the natural history of diabetes and the objective of evaluation should be all taken into account.
