Study on the specific autoantibody in nonimmune thrombocytopenia in malignant tumor
- VernacularTitle:恶性肿瘤非免疫性血小板减少患者血小板特异性抗体的研究
- Author:
Yahong SUN
;
Li LI
;
Ming HOU
;
Ping QIN
;
Yan ZHANG
- Publication Type:Journal Article
- Keywords:
Malignant tumor;
Thrombocytopenic;
Idiopathic;
Antigen platelet;
MAIPA
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the possibility of the exist of specific antibody against platelet in tumor patients and to evaluate the value of MAIPA in measure of specific antibody against platelet in malignant tumor patients with nonimmune thrombocytopenic purpura. Methods Anti- GPⅡb/Ⅲa and anti- GPⅠb/Ⅸ autoantibodies were detected by a modified monoclonal antibody immobilization of platelet antigens assay(modified MAIPA). Results The positive rate of the platelet antibody in nonimmune thrombocytopenic purpura is very low with MAIPA. Conclusions The platelet GP- specific autoantibody detection is considerably important in discriminating immune from nonimmune thrombocytopenia.
