Detection and clinical significance of serum vascular endothelial growth factor in patients with malignant tumor
- VernacularTitle:恶性肿瘤患者血清VEGF的检测及临床意义
- Author:
Qihui CHENG
;
Shuhua SUN
;
Xianxia MAI
;
Xinai LI
- Publication Type:Journal Article
- Keywords:
Tumor;
Vascular endothelial growth factor (VEGF);
ELISA
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical applied value of serum vascular endothelial growth factor (VEGF) in therapeutic process of patients with malignant tumor. Methods Serum VEGF levels and positive rates were measured by ELISA in 337 untreated cancer patients, 25 postoperative and 22 recurring postoperative patients with malignant tumor, while 47 benign tumor and 61 healthy individuals as controls. Results Serum VEGF levels and positive rates were significantly higher in patients with various malignant tumors than in benign tumors and healthy controls (P 0.05). Conclusions It was helpful to get a message of pathogenetic condition of malignant tumor patients whose serum VEGF was dynamically monitored.
