Long-term outcomes of immunosuppressive agents in treating myasthenia gravis in the aged
- VernacularTitle:老年重症肌无力患者免疫抑制疗法的远期疗效分析
- Author:
Shunlun WAN
;
Hao SUN
;
Hongyan WANG
;
Zhiqiang CONG
- Publication Type:Journal Article
- Keywords:
Aged;
Myasthenia gravis;
Immunosuppression;
Treatment outcome
- From:
Chinese Journal of Neurology
1999;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the long-term outcomes of immunosuppressive agents used for myasthenia gravis(MG) patients with disease onset after or at 60. Methods Long-term outcome was evaluated in 99 cases with following-up longer than 1 year. Remission, pharmacological remission, and marked improvement were considered as good results or good long-term outcome. Results All good results were recorded in 79 MG patients (79.8%) receiving immunosuppressive treatments. 48 patients had been treated with glucocorticoids (GC) alone, of them, 35(72.9%) achieved good results. 8 of them having a complete remission for 18 to 67 months (averaging (54.8?19.8) months). 16 patients got pharmacological remission for 7 to 37 months (averaging (15.7?8.0) months). MG patients in different gender had different responses to GC. The good long-term outcome was found in 83.3% (25/30) males and only 55.6% (10/18) in females with GC therapy. There was a rate statistically higher in male than in female patients (P
