Distribution of epidermal growth factor in transition zone and peripheral zone of human normal prostate
- VernacularTitle:表皮生长因子在前列腺带性结构中的分布及意义
- Author:
Hongbin SUN
;
Shujie XIA
- Publication Type:Journal Article
- Keywords:
Prostate;
Transition/peripheral zone;
Epidermal growth factor
- From:
Chinese Journal of Urology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the regional differential expression of epidermal growth factor(EGF)in transition/peripheral zones of human normal prostate. Methods RT-PCR was used to determine semi-quantitatively the expression of EGF mRNA in 17 specimens of peripheral /central zones from normal prostates and 20 specimens of periurethral zone from BPH.EGF protein expsession was examined with Western blot. Results In normal prostate tissue,EGF mRNA level in transition zone was significant higher than that in peripheral zone (0.96?0.31 vs 0.53?0.27,respectively,P
