Effects of pentifylline on hypertrophic scars in rabbit ears
- VernacularTitle:己基可可碱对兔耳瘢痕组织的作用
- Author:
Meilian WU
;
Shaojun LUO
;
Shaoming TANG
;
Li LIANG
;
Gang ZHANG
- Publication Type:Journal Article
- Keywords:
Pentifylline;
Hypertrophic scar;
Animal model
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of pentifylline on hypertrophic scars in the rabbit ears. Methods An animal model for hypertrophic scars was established and treated with pentifylline in different concentrations or saline on day 49. Hypertrophic index, growth of fibroblasts and production of collagen in the section were quantitatively determined with an image analysis system. Results Hypertrophic index was found to be decreased in the pentifylline-treated group (P