Spatial and temporal features of proliferating vessels during mandibular distraction osteogenesis
- VernacularTitle:下颌牵张成骨过程中血管生成和血供重建的立体形态构筑
- Author:
Jihua LI
;
Jing HU
;
Dazhang WANG
- Publication Type:Journal Article
- Keywords:
Distraction osteogenesis;
Mandible;
Angiogenesis
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the spatial and temporal features of p roliferating vessels during mandibular distraction osteogenesis. Methods :Bilateral mandibles of twelve adult goats were lengthened by 10 mm wit h a custom-made distractor at 1 mm/d, two animals were killed at each intervals . Two additional goats were used as normal control. SEM microvascular corrosion casting was used to examine the spatial and temporal features of proliferative v essels within distraction gap. Results:During distraction perio d, numerous vessels from bone marrow and periosteum were regenerated into distra ction gap and began to form vascular network. In the early phase of fixation per iod, the orientation of vein sinus was in accord with distraction orientation. A long with the time, more vessles were connected, regeneration of vessels vanishe d, and the vascular system within distraction gap became more mature.Con clusion:Angiogenesis during DO is closely related to the osteogenesis; the blood supply of new bone in distraction gap is from both bone marrow and per iosteum.
