Expression of basic fibroblast growth factor and its relationship with angiogenesis in oral squamous cell carcinoma
- VernacularTitle:口腔鳞癌组织中bFGF的表达与血管生成的关系
- Author:
Xianlu ZHUO
;
Yufeng SONG
- Publication Type:Journal Article
- Keywords:
bFGF;
Mouth;
Squamous cell neoplasms;
Angiogenesis
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the role of basic fibroblast growth f ac tor (bFGF) on angiogenesis in oral squamous cell carcinoma(OSCC).Methods :Expression of bFGF and CD34 in 42 cases of OSCC(14 cases with lymph no de metastasis) and 10 cases of normal oral mucosa(NOM) was detected by immunohis tochemistry. Microvessel density(MVD) in OSCC was assessed with microscope. Results:bFGF was detected in 29(69.05%) cases of OSCC and in 3(33.3 3%) of NOM. MVD in OSCC and NOM was 53.50?9.59 and 23.30?7.33(P
