Interleukin-8 content in GCF and its relationship with subgingival Porphyromo nas gingivails in patients with chronic periodontitis
- VernacularTitle:牙龈卟啉单胞菌与龈沟液中白细胞介素8关系的研究
- Author:
Jing ZHAO
;
Jincai ZHANG
;
Yunhui ZHANG
- Publication Type:Journal Article
- Keywords:
Interleakin-8;
Gingival crevicular fluid;
Porphyromonas.gingivalis;
Chronic periodontitis
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the levels of IL-8 i n GCF in patients with chronic periodontitis and their relationship with subgingi val Porphyromonas gingivalis(Pg).Methods:10 GCF samples from periodontal healthy volunteers, 60 from the teeth with chronic periodontiti s in patients and 10 from the periodontal healthy teeth in the patients with chr onic periodontitis were collected. Subgingival plaque samples and clinical data on GI, PPD and CAL were obtained. A sensitive ELISA was used to measure IL-8 in GCF and a PCR method was employed to measure the amount of Pg.Resul ts:①Higher total amount of IL-8 in GCF was found in chronic periodonti tis subjects than that in healthy volunteers(P0.05). ②There was positive correlation between the total amount of IL-8 and clinical parameters (GI, PPD, CAL).③There was no correlation between the amount of Pg and the concentration or total amount of IL-8. Conclusions:I L-8 increases with the increace of GCF in the patients with chronic periodontit is, but is not related to Pg in subgingival plaque.
