Changes of Myoepithelial Cells in Mammary Atypical Hyperplasia and Breast Cancer
- VernacularTitle:乳腺不典型增生和乳腺癌中肌上皮细胞的变化及意义
- Author:
Xiaorong HAN
;
Jun JIANG
- Publication Type:Journal Article
- Keywords:
Atypical hyperplasia Breast neoplasm Myoepithelia cell Actin
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of myoepithelial cells in mammary atypical hyperplasia and breast cancer. Methods SP immunohistochemistry was used to detect actin expression in normal breast tissue, grade Ⅰ, Ⅱ and Ⅲ atypical hyperplasia and breast cancer. Electromicroscopy was used to observe the changes of ultrastructure of myoepithelial cells. Results Actin was only detected in myoepithelial cells of normal breast tissue and grade Ⅰand Ⅱ atypical hyperplasia. The positive expression rates of actin in grade Ⅲ atypical hyperplasia(70%) and breast cancer(90%) were significantly higher than that in grade Ⅱ atypical hyperplasia(10%), P
