Detection of Borna disease virus P24 fragment from peripheral blood cells in patients with viral encephalitis
- VernacularTitle:病毒性脑炎患者Borna病病毒P24基因片段的检测
- Author:
Ping XU
;
Peng XIE
;
Dezhi ZOU
- Publication Type:Journal Article
- Keywords:
Encephalitis,viral;
Borna disease virus;
Viral proteins;
RNA,viral
- From:
Chinese Journal of Neurology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the relationship between Borna disease virus (BDV) and the human viral encephalitis.MethodsThe P24 fragment of BDV RNA in peripheral blood mononuclear cells (PBMC) from 59 patients with viral encephalitis diagnosed clinically, and 112 healthy donors were examined by fluorescence quantitative nested reverse transcriptase polymerase chain reaction (FQ-nRT-PCR).ResultsThere were 3 positive of BDV P24 fragment in 59 patients with viral encephalitis, and no positive in blood donors. The positive rate of BDV p24 in PBMC in viral encephalitis (5.08%) was higher significantly than that in blood donors (P
