Detection of nucleic acid and antibody to chlamydia pneumoniae in coronary atherosclerotic heart disease
- VernacularTitle:冠心病患者肺炎衣原体DNA及抗体检测
- Author:
Wenling JIANG
;
Yunyun SUN
;
Xianling LUO
;
Jiyan CHEN
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Chlamydia pneumoniae;
Nucleic acid;
Antibody
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the state of Chlamydia pneumoniae (Cpn) infection in patients with coronary hear disease (CHD), and explore the relationship between Cpn infection and the gonesis and progressin of CHD.Methods:By means of PCR and ELISA, Cpn IgG antibody and nucleic acid were detected in 159 patients with CHD and 41 control subjects.Results:The positivity rate of Cpn DNA was 43 40%(69/159) in the patient group and 7 32%(3/41) in the control group, showing obvious difference between the two groups( P
