Oxidative Damage in the Tissues of Rats Induced by Rice Harvested in Mercury Mining Area
- VernacularTitle:汞矿地区大米对大鼠生长发育及氧化损伤的影响
- Author:
Guiwen JIN
;
Xiuling JI
;
Jing LU
- Publication Type:Journal Article
- Keywords:
Mercury;
Rice;
Rat;
Lipid peroxidation
- From:
Journal of Environment and Health
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the growth and oxidative damage of rats exposed to mercury mining area rice. Methods The rats were exposed to the rice harvested in mercury mining area or in other area for 90 days, and then determined the change of their weight, the activity of SOD and GSH-Px, the content of MDA and GSH in brain, liver and kidney tissue. Results After 90 days of exposure, compared with the control,significantly higher weight,higher level of MDA,lower activities of GSH-Px,SOD and lower level of GSH were found in brain, liver and kidney tissue of the rat of exposure group. Conclusion The results of the present paper show that the rice contaminated by mercury in this mercury mining area may induce lipid peroxidation in the rat's in brain, liver and kidney tissue.
