The protective effect of synthetic cordyceps Sinensia Sacc powder on the liver grafts of rats
- VernacularTitle:人工冬虫夏草菌粉提高大鼠肝脏保存质量的实验研究
- Author:
Tie FANG
;
Long LI
;
Jinzhe ZHANG
;
Qingxi ZHANG
- Publication Type:Journal Article
- Keywords:
preserved injury;
Cordyceps Sinensia Sacc;
apoptosis;
HPLC;
TUNEL
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effect of the extractions of synthetic Cordyceps Sinensia Sacc powder on cold preserved injured tissues of rat livers. Methods The extractions of synthetic Cordyceps Sinensia Sacc powder were added into LR at certain proportion. Having been preserved for 6 or 12 hours, the liver grafts of rats were reperfused for 30 minutes. And then, ATP, ADP, AMP in livers were measured and added up to total adenine nucleotide (TAN). Besides, AST, ALT, MDA, and ET in the effluent of the reperfusion were assayed. Pathological sections were studied and apoptosis index was detected by TUNEL method. Results The values of ATP, TAN in the experimental group preserved for 12 hours were significantly higher than the control group (P0.05), but the mean of the former was higher than the latter. There was obvious increase of apoptosis index (P
