Expression of heat shock protein 27 mRNA in the carcinogenesis of esophageal squamous epithelium
- VernacularTitle:热休克蛋白27基因在食管鳞状上皮癌变过程中的表达
- Author:
Fumin CAO
;
Xianghong ZHANG
;
Lingxiao XING
- Publication Type:Journal Article
- Keywords:
esophageal carcinoma;
atypical hyperplasia;
heat shock protein mRNA
- From:
China Oncology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions:Compared with normal esophageal mucosa, the expression of HSP27 mRNA in esophageal squamous carcinoma and mucosa with atypical hyperplasia was markedly decreased.This indicated that the expression of HSP27 mRNA to a greater or less extent lost in the carcinogenesis and development of esophageal squamous carcinoma. To up-regulate the expression of HSP27 mRNA in esophageal squamous carcinoma may be a very effective biological therapy.