Advances in research of tumor infiltrating dentritic cells
- VernacularTitle:肿瘤浸润性树突状细胞的研究进展
- Author:
Qi WANG
;
Ping LIN
- Publication Type:Journal Article
- Keywords:
tumor infiltrating dendritic cells;
tumor prognosis;
molecular expression of DC
- From:
China Oncology
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
As antigen-presenting cells, DCs are the most potent and unique,they can stimulate the primitive T cells. They play a major role in initiating the immune response. Tumor infiltrating dendritic cells (TIDCs) can reflect the antitumor immune capability of the host. The density of TIDC perhaps is associated with the prognosis in some cancers. The disablement of TIDCS is partly due to the phenotype they have. Perhaps it is the immunosuppressive factors secreted by tumor cells that have changed their phenotype.The studies about TIDCs provide the basis for DC-mediated antitumor immune therapy,and suggest the use of DC to treat tumors through different approaches.
