Expression of apoptosis regulatory protein survivin in pituitary adenomas
- VernacularTitle:凋亡抑制蛋白survivin在垂体腺瘤中的表达
- Author:
Peihong SHEN
;
Jie MA
;
Kuisheng CHEN
;
Yunhan ZHANG
- Publication Type:Journal Article
- Keywords:
Pituitary adenomas;
Immunohistochemistry;
Survivin;
Proto-oncogene proteins c-bcl-2
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The expressions of survivin and bcl-2 protiens were examined in 8 specimens from normal pituitary tissues and 38 pituitary adenomas by immunohistochemistry. The results showed that the expression of survivin was strongly associated with bcl-2 expression and abnormal expression of survivin resulted in inhibition of cell apoptosis, which might play a role in the pathogenesis of pituitary adenomas.
