Effects of Acute Low Temperature and Hypoxia on Serum SOD Activity and MDA Content of Myocardial Ischemia Rabbit
- VernacularTitle:急性低温低氧复合环境对心肌缺血家兔脂质过氧化的影响
- Author:
Junjie HUANG
;
Shanmin ZHAO
;
Xianjiao HE
- Publication Type:Journal Article
- Keywords:
Myocardial ischemia;
Acute low temperatur;
Acute hypoxia;
Superoxide dismutase;
Malondialdehyde
- From:
Journal of Environment and Health
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of acute low temperature and hypoxia on serum SOD and MDA of myocardial ischemia rabbit. Methods 24 rabbits were randomly divided into 3 groups, such as normally low tamperature and hypoxia group, myocardial ischemia normal temporature and normal oxygen group and myocardial ischemia low temporature and hypoxia group. Put myocardial ischemia rabbits into the condition in which low temperature(-10?2) ℃ and hypoxia (oxygen content 8.5% ) existed, superoxide dismutase (SOD) activity and malondialdehyde (MDA) contents were measured after an hour. Results Serum SOD activity were decreased significantly in acute low temperature and hypoxia compared with normal temperature and normal oxygen pressure (P
