Mechanism of Tributyltin-Induced Apoptosis
- VernacularTitle:三丁基锡诱导细胞凋亡的机制
- Author:
Xin ZHU
;
Lihong XU
- Publication Type:Journal Article
- Keywords:
Tributyltin;
Apoptosis;
Mitochondria;
Calciumion;
Reactive oxygen species;
Cytochrome C;
Caspase
- From:
Journal of Environment and Health
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Extensive use of tributyltin (TBT) has caused serious environmental pollution, which is harmful to human and other organisms. As a cytotoxic chemical, an important mode for TBT effects on the cells is to induce apoptosis. The present paper mainly reviewed the mechanism by which TBT induces apoptosis at low concentration.