Diagnosis and treatment of Hashimoto’s disease complicated with thyroid cancer
- VernacularTitle:桥本氏病合并甲状腺乳头状腺癌
- Author:
Jianping YU
;
Runhao CHEN
;
Liu GUI
- Publication Type:Journal Article
- Keywords:
Hashimoto disease;
thyroid neoplasms;
autoimm une diseases;
operative
- From:
China Oncology
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To investigate the pathogenesis,diagnos is and treatment of hashimoto's disease(HD) complicated with papillary thyroid c ancer (PTC ). Methods:Clinical data of 12 cases of HD complicated with PTC un dergoing surgery were analysed retrospectively and followed-up for one half to 8 years. Results:In this series papillary thyroid cancer occurred in 25 % (12/48) in patients with HD, but correct preoperative diagnosis was obtained i n 3 (25%) of 12 cases.All patients had thyroid nodules and received thyroidectom y,3 cases underwent functional cervical clearance of lymph nodes. All patients w ere followed up for 6 months to 8 years and there was no death , no recurrence and no metastasis. Conclusions:HD can develop into PTC .The clinical diagnosis of coexistence of HD and PTC is still difficult. The key to diagnosis and rational treatment includes detailed understanding its clinical features, routine examin ation of serum antibodies and ultrasonography, selected scintigraphic thyroid s can or FNAB and finally quick frozen pathologic section in operation. HD complic ated with PTC should be treated surgically.Intraoperative frozen section diagnos is should be performed routinely so that HD complicated with PTC can be diagnose d.The operation procedure should be individualized.All patients should be given small dosage of thyroxine.
