The Clinical significance of urine transferrin in the type 2 diabetic nephropathy and primary chronic glomerular disease
- VernacularTitle:转铁蛋白在糖尿病肾病和原发性慢性肾小球疾病中的临床意义
- Author:
Aiping YIN
;
Ling DONG
;
Yanting GAO
- Publication Type:Journal Article
- Keywords:
transferrin;
UAER;
DN;
CGD
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of urine transferrin in the type 2 diabetic nephropathy and primary chronic glomerular disease. Methods The level of TRF and UAER in the urine of 114 patients with type 2 diabetes mellitus (T2DM), 108 patients with CGD and 30 healthy patients was measured by rate nephelometry and analyzed. Results Urine TRF significantly increased earlier than ALB at the early stage of DN; Linear correlation was found by correlation analysis between the level of TRF in urine level and the quantity of protein in urine. Conclusion TRF in urine obviously increased at the early stage of DN. It was more sensitive than UAER to reflect the early renal injury of DM. A statistically significant correlation was found between the TRF level and the quantity of protein in the urine.
