An experimental study on revascularization after vascularized bone allograft
- VernacularTitle:吻合血管的同种异体骨移植后移植物再血管化的研究
- Author:
Shengxiang TAO
;
Zhenguang CHEN
;
Yun XIE
;
Xiaohui ZHENG
;
Yuhua YANG
- Publication Type:Journal Article
- Keywords:
Bone graft;
Revascularization;
Microsurgieal technigue;
Rabbit
- From:
Chinese Journal of Microsurgery
2008;31(2):119-121,illust 7
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To explore the process and regularity of graft after vascularized bone allograft. Methods An adult rabbit model of massive femoral defect was established and reconstmcted with vascularized bone allograft based by laterial rotating femoral vessel.The experiments were carried out in two groups,the experimental group(vascularized bone allograft)and the control group(nonvascularized bone allograft).Then observation on periosteum,cortex and marrow was performed after operation containing in ink-infused specimen. Results The revascularization in the experimental grouD was observed synchronicly on periosteum,cortex and marrow after operation,while the phenomenon of vascularization took place from periosteum to marrow in the control group.The density of micro-vessel in experimental group were 10.0±1.8,15.8±1.5 and 13.8±1.5,13.8±1.5 respectivly after 2,4,8 and 16 weeks.and those were 2.8±0.8,6.0±0.9,5.5±1.0,6.0±1.1 in control group.The ink-infused experiment demonstrated a better revascularization in the experimental group. Conclusion The vaseularization can promote revascularization of graft during bone allograft.
