Comparison of memory B cell polyclonal activation by different phylogeny antigens
- VernacularTitle:记忆性B细胞多克隆激活模式与激发抗原种属特异性
- Author:
Hui LIU
;
Hong LUO
;
Liyun GONG
;
Zhun WANG
- Publication Type:Journal Article
- Keywords:
Immune response;
Immunologic memory;
Nonspecific immunity
- From:
Chinese Journal of Immunology
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To characterize the memory B lymphocytes activalion by nonspecific antigen of different phylogeny antigen.Methods:Three groups were immunized by same quantity different antigens,which were ovalbumin,milk and ostrcean extract to intitule A,B,C,respectively,as basic immunity.After one week,across immunity was performed with A,B and C antigen as secondary immunity,the subgroups were divided.Basic antibodies were determined with ELISA before and after secondary immunity.Results:Antibodies after secondary immunity increase 10%~25% than that before secondary immunity in subgroups which antigens were different when basic and secondary immunity.There were significant difference compare with control groups (P