Expression and correlation of E-cadherin and CD44V6 in oral squamous cell carcinoma
- VernacularTitle:E-cad、CD44V6在口腔鳞癌组织中的表达及其相关性研究
- Author:
Jian LIU
;
Jianhong PU
;
Zili GE
- Publication Type:Journal Article
- Keywords:
E-cadherin;
CD44V6;
Oral squamous carcinoma;
Imm unohistochemistry
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expressions of E-cadherin(E-cad) an d CD44V6 in normal oral mucous,oral atypical hyperplasia and oral squamous cell carcinoma(OSCC).Methods:The expression of E-cad and CD44V6 in 1 7 cases of normal oral mucous,6 of oral atypical hyperplasia and 52 of OSCC was examined with immunohistochemistry. Results: E-cad expression was observed in all the cases of normal oral mucous and oral atypical hyperplasi a,and in 43/52( 82.69% ) of OSCC. CD44V6 expression was observed in all the ca ses of normal oral mucous and oral atypical hyperplasia,and in 32/52(61.54%) of OSCC.In OSCC, the expression of E-cad was decreased with the decrease of differ entiation degree(P
