Expression of tumor necrosis factor receptor-associated factor 6 in rat develop ing dental germ
- VernacularTitle:TRAF6在大鼠牙胚发育过程中的表达
- Author:
Xia LI
;
Mingzhen XIAO
;
Qing YU
- Publication Type:Journal Article
- Keywords:
Tumor necrosis factor receptor-associat ed factor 6;
Dental germ;
Immunohistochemistry
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the function of tumor necrosis factor r eceptor-associated factor 6(TRAF6) in the development of rat dental germ. Methods:After specimen preparation of every stage of rat developing d ental germs, immunohistochemical staining of TRAF6 was carried out. Resu lts:Positive expression of TRAF 6 was observed in thickening stage of de ntal lamina, peripheral dental lamina of bud stage, outer and inner enamal epith elium, stellate reticulum,dental papilla cells and dentinoblasts in early bell s tage, ameloblasts, dentinoblast,intermediate layer, stellate reticulum and denta l papilla cells in late bell stage, and dentinoblasts and ameloblasts in the ger m 7 days after birth. Conclusions:TRAF6 may be a signal transduc tion factor which modulates the proliferation and differentiation of developing epithelial and mesenchymal cells in the development of the dental germ.
