Circannual rhythms of parathyroid hormone-related protein in growing rats after functional mandibular protrusion
- VernacularTitle:前伸大鼠下颌后髁突局部甲状旁腺激素相关蛋白含量的季节性变化规律
- Author:
Jiangning LI
;
Yangxi CHEN
;
Zhengrong WANG
- Publication Type:Journal Article
- Keywords:
Functional treatment;
Cirannual rhythms;
PTHrP (P arathyroid Hormone-related Protein)
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the levels of parathyroid hormo ne -related protein(PTHrP) in mandibular condylar cartilage during mandible forwar d positioning in different seasons. Methods:64 SD rats were rand omly divided into four groups according to seasons. Orthodontic appliance was us ed in 32 rats for 12 hours each day in daytime for mandibular protrusion. 8 rats were sacrificed at each season time point.Condyle samples were processed for PT HrP detection by a two-site immunoradiometric assay (IRMA) method.Another 32 ra ts without treatment were used as the controls.Macroscopic and microscopic appro ach were applied to analyze the results. Results:The level of P THrP in mandibular condylar cartilage(MCC) in the group of orthodontic treatmen t was higher than that in the control group(P
