Thymidine phosphorylase expression in tumor stroma of oral squamous cell carcinoma
- VernacularTitle:胸苷磷酸化酶在口腔鳞癌基质中的表达及其与血管形成的关系
- Author:
Tianhong FU
;
Jingshu GENG
;
Naisong ZHANG
- Publication Type:Journal Article
- Keywords:
Oral squamous cell carcinoma;
Thymidine phosphory lase;
Microvessel density;
Immunohistochemical
- From:
Journal of Practical Stomatology
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the correlation of thymidine phosphory la se(TP) expression with histological parameters and microvessel density(MVD) in t umor stroma of oral squamous cell carcinoma(OSCC).Methods:52 cas es of oral squamous cell carcinoma and 10 cases of normal oral mucosa were immun ohistochemically stained with a SP method by using monoclonal antibody of TP and FⅧ-RA.The correlation of TP expression with the clinical data and MVD in tumo r stroma was analyzed.Results: The expression of TP in oral squa mous cell carcinoma was much higher than that in normal oral mucosa (P0.05).There was a positive correlation between the TP expression an d MVD(P
