The protective effect of Resvaratrol on myocardial ischemic-reperfused induced injury in rats
- VernacularTitle:白藜芦醇对心肌缺血再灌注损伤的保护作用
- Author:
Wei HUANG
;
Juntian LIU
;
Yuhai TANG
;
Honglang LIU
;
Xiaolian SHI
;
Aiqun KANG
- Publication Type:Journal Article
- Keywords:
resvaratrol;
myocardial ischemic/reperfusion inju ry;
myocardial infarction;
salvia milticrrhiaze
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effect of Res o n myocardial ischemic/reperfused induced injury. Methods My ocardial ischemic/reperfusion model was used to study the protective effect of d ifferent dosage resvaratrol on myocardial ischemic/reperfusion injury in rats. Results Res shrinked the size of myocardial infarction indu ced by the ischemic reperfused method, inhibited the release of creatine kinase( CK) and lactate dehydrogenase(LDH) from the injured myocardium and reduced elega ted ST-T of electrocardiogram(ECG) caused by myocardial ischemic-reperfused in jury in dose-dependent way. Res also improved the morphological changes of inju red myocardium. Conclusion Res has protective action on myo cardial ischemic reperfused injury in rats.
