Active components in the extracts of Radix Salvia miltiorrhizae by supercritical carbon dioxide fluid
- VernacularTitle:CO_2超临界流体萃取丹参中的有效成分
- Author:
Xia LI
;
Yuhai TANG
;
Xinfeng ZHAO
;
Hongbo LU
;
Xiaohui ZHENG
- Publication Type:Journal Article
- Keywords:
Radix Salvia miltiorrhizae;
SFE-CO 2;
HPLC-MS n
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the ex tr action technique for seperating the active components in the root of Salvia mi ltiorrhizae bunge by supercritical fluid, and to analyze the extracted product s by HPLC-MS n . Methods The extraction condition s were established as follows: 950ml?L -1ethanol as the first entrainer, t he pressure of 20.0 MPa, temperature at 45 ℃, and extracting time 1 h; then 100 mL?L -1 ethanol was selected as the second entrainer, pressur e was 30.0 MPa, temperature was 65 ℃, and extracting time was 3 h. Results Compared with traditional refluxing extraction and ultrasonic extraction, supercritical fluid extraction was better and more effect ive. Conclusion Supercritical extraction is simple, highly selec tive and efficient in extracting the active components in Salvia miltiorrhizae bunge.
