Association of interleukin-1?, 4, 6, TNF-? gene polymorphisms with Hashimoto′s thyroiditis
- VernacularTitle:白细胞介素1?、4、6、TNF-?基因多态性与桥本甲状腺炎的关系
- Author:
Ling JIANG
;
Ying GONG
;
Weiyan JIANG
;
Wei QU
;
Xiaoli ZHANG
;
Chuanlong WU
- Publication Type:Journal Article
- Keywords:
Thyroiditis, autoimmune;
Polymorphism (Genetics);
Interleukins;
Tumor neorosis factor-?
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The association of the polymorphisms of interleukin (IL)-1?, IL-4, IL-6, tumor necrosis factor-? (TNF-?) gene with Hashimoto′s thyroiditis (HT) in Shandong population of China was investigated. The results showed that the frequency of the t allele in the promoter region of IL-4 at position -590 in HT group was significantly lower than that in control group (0.060 vs 0.155, P
