Effect of angiotensin Ⅱ receptor antagonist on the plasma levels of calcitonin gene-related peptide and endothelin in the patients with diabetic nephrophy
- VernacularTitle:血管紧张素Ⅱ受体拮抗剂对糖尿病肾病患者降钙素基因相关肽、内皮素水平的影响
- Author:
Cuiping CAO
;
Guoliang LIU
;
Binhong WEN
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
Calcitonin gene-related peptide;
Endothelin;
Angiotensin Ⅱ receptor antagonist
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The plasma levels of calcitonin gene-related peptide (CGRP) and endothelin (ET) were assayed in 76 patients with diabetic nephropathy (DN) and 23 healthy subjects, and the changes of CGRP and ET levels after treatment with angiotensin Ⅱ receptor antagonist (ARBS) were observed. The results showed that CGRP level was increased and ET level decreased after treatment with ARBS, which seemed to delay the onset and development of DN.
