Evaluation of intraoral distraction osteogenesis by scanning electron microscopy and mineral content
- VernacularTitle:口内牵引成骨修复下颌骨缺损的扫描电镜研究
- Author:
Liu BING
;
Zhu LI
;
Li NING
- Publication Type:Journal Article
- Keywords:
Distraction osteogenesis;
Mandibular defect;
Animal model;
Scanning electron microscopy
- From:
Journal of Practical Stomatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the ultrastructural characters and mineral content of the newly formed bone induced by distraction osteogenesis(DO) in the canine mandibular defects.Methods:4 beagle canines were used to establish 2.0 cm segmental mandibular defect surgically. Intraoral bifocal distraction osteogenesis was used to repaire the defects. After a 10-day latency, the transport disc was advanced at a rate of 0.5 mm? 2/day until the bone fragment was docked at the planned position. Specimen retrieval at 35 weeks after completion of distraction, scanning electron microscopy(SEM) analysis was then performed. The mineral content was measured by electron dispersive spectroscopy.Results:35 weeks after application of DO the mandibular defects were completely filled with regenerated bone. The regenerated bone was compact, sturdy and mature. The new bone was closed to the transport disk. The Ca/P content ratio was 1.80 in the regenerated bone and 2.02 in the transport disk.Conclusion: DO may induce new bone formation and may be used to repaire mandibular defects.
