Study of using urokinase for injection to lysis endometriosis ovarian cyst under sonography guided puncture
- VernacularTitle:超声引导尿激酶溶解子宫内膜异位囊肿的研究
- Author:
Jing ZHANG
;
Jinshan GAO
;
Junyan WANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Endometriosis;
cysts;
Urokinase
- From:
Chinese Journal of Ultrasonography
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for lysis coagula rapidly within endometriosis cyst to ease aspiration difficulty while ultrasound-guided puncture and aspiration therapy. Methods Urokinase for injection with different concentration was used to lysis the coagula within endometriosis ovarian cyst with thick content. The effect of urokinase on the coagula, the wall of cyst and the aspiration rate of content were investigated. Results The area of coagula in unit area was significantly small in urokinase group compared with that in control group[( 95.6? 17.5)?m2 vs ( 1692.3? 1028.3)?m2,F= 28.86,P= 0.000]. Urokinase can lysis the coagula appending to the wall but did not change the permeability of cyst wall. The aspiration rate was significantly faster in urokinase group than in control group[( 2.79? 2.61)ml/min vs ( 1.42? 0.58)ml/min; t= 2.4572,P= 0.0121]. Conclusions Urokinase can resolve the coagula within endometriosis ovarian cyst and on the cyst wall safely and effectively, making it easy for cyst content aspirating and improving the coagulation effect of ethanol.
