Prenatal ultrasonographic evaluation of midline facial defects of holoprosencephaly
- VernacularTitle:全前脑面部畸形的产前超声诊断
- Author:
Shengli LI
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Holoprosencephaly
- From:
Chinese Journal of Ultrasonography
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the prenatal ultrasonographic evaluation on fetal midline facial defects of holoprosencephaly. Methods Twenty-four facial malformations of 14 cases with alobar/semilobar holoprosencephaly from August 2000 through April 2004 were reviewed to determine and classify the associated facial abnormalities detected with prenatal sonography. Results There were 24 facial abnormalities in 14 cases with alobar/semilobar holoprosencephaly. Facial abnormalities were present in all cases and were detected in 22 ( 91.7%) of 24 facial malformations on prenatal sonography. One or more extrafacial anomalies were present in 8 ( 57.1%) of 14 fetuses. Conclusions Prenatal sonographic evaluation of midline facial defect may allow more definitive diagnosis of alobar or semilobar holoprosencephaly.
