Protective Effects of Aescin on Rat Liver in Acute Pancreatitis
- VernacularTitle:防治急性胰腺炎并发肝脏损害的实验研究
- Author:
Jinbiao LIU
;
Zhenxiang YAO
;
Shengchun LIU
- Publication Type:Journal Article
- Keywords:
Pancreatitis Liver Aescin
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the liver injury and effects of aescin on liver in rats with acute pancreatitis. Methods The rats were divided into 3 groups (control group, AP group and aescin group). The serum alanine aminotransferase (ALT), serum lactate dehydrogenase (LDH), hepatic cellular energy charge (EC) and adenosine triphosphate (ATP) were detected. The pathologic changes in pancreas and liver were also observed. Results The serum levels of ALT and LDH in aescin group were significantly lower than those of the AP group. The EC and ATP levels were significantly higher in aescin group than that of the AP group. Conclusion Introvenous injection of aescin can alleviate the liver injury in rats with acute pancreatitis.
