The Oxidative Stress State of Mice After Air Simulated Diving
- VernacularTitle:空气模拟潜水后小鼠的氧化应激状态研究
- Author:
Haisheng WU
;
Weigang XU
;
Kaizhong TAO
- Publication Type:Journal Article
- Keywords:
Diving;
Glutathione;
Glutathione-s-transferase;
Glutathione peroxidase;
Superoxide dismutase;
Maleic dialdehyde;
Catalase;
Oxidative stress
- From:
Journal of Environment and Health
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the oxidative stress state of mice before and after air simulated diving. Methods Forty-eight mice were divided into 6 groups randomly. Every group was exposed to corresponding pressure for 60 minutes, twice a day for consecutive 3 days. Blood was obtained at the corresponding time to observe the changes of maleic dialdehyde, glutathione, glutathione-s-transferase, glutathione peroxidase, superoxide dismutase and catalase. Results Compared with the control, the activity of glutathione-s-transferase, glutathione peroxidase, superoxide dismutase, catalase and the level of glutathione were markedly inhibited and maleic dialdehyde increased in HO group and HA1 group (P