The comparison research of intrathecal injection of oxygen and hyperbaric oxygen on the rehabilitation of patients with craniocerebral injury
- VernacularTitle:鞘内给氧与高压氧对颅脑损伤患者神经功能恢复的对比研究
- Author:
Ligui GAO
;
Huifang WANG
;
Wei SHI
;
Ruizhi WANG
- Publication Type:Journal Article
- Keywords:
craniocerebral injury;
lumbar puncture;
hyperbari c oxygen
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of intrathecal i njection of oxygen in the treatment of patients with craniocerebral injury throu gh the comparison research of intrathecal injection of oxygen and hyperbaric oxy gen on the rehabilitation of patients with craniocerebral injury. Methods A total of 150 patients were divided into three gro ups: the group of intrathecal injection of oxygen, the group treated with hyperb aric oxygen and the group of intrathecal injection of air. CSF was applied via l umbar puncture. The rehabilitative function of patients was observed and the lev el of superoxide dismutase (SOD), malondialedhyde (MDA), and nitrogen monoxide ( NO) in CSF were measured. Results The neurological function of the patients treated w ith oxygen injected intrathecally intrathecal injection of oxygen was improved w as more significanty than that of patients treated with hyperbaric oxygen; the i ncrease of SOD, NO and the decrease of NO were more significant than that in the group treated with hyperbaric oxygen. Conclusion Intrathecal injection of oxygen can improve the rehabilitative function more significantly than the hyperbaric oxygen therapy in the treatment of craniocerebral injury.
