The chemotherapy of oxaliplatin combined with capecitabine in advanced gastric cancers
- VernacularTitle:草酸铂联合卡培他滨治疗晚期胃癌的近期疗效分析
- Author:
Jianhua MIAO
;
Shubo CHEN
;
Jiawei ZHANG
- Publication Type:Journal Article
- Keywords:
gastric cancer;
oxaliplatin;
capecitabine;
chemotheraphy
- From:
China Oncology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Purpose:To evaluate the short-term effect of combination chemotherapy of oxaliplatin plus capecitabine on advanced cancer.Methods:32 patients of advanced gastric cancer were treated with oxaliplatin plus capecitabine for 76 weeks.Results:There were 6 CR, 16 PR, 8 NC, 2 PD, in our group and the overall response rate was 68.75% (22/32). The median alleviative time was 8 months, the median survival time was 12 months and the one-year survival rate was 55%. 30(93.75%) patients benefited from this method. The side effects were all tolerable which were alleviated by active therapy. There was no death and nobody stopped chemotherapy because of side effects.Conclusions:Combination chemotherapy of oxaliplatin plus capecitabine to treat advanced gastric cancers was certainly effective and tolerable to toxicities. This chemotherapy will be used as the first-line in more patients and is worthy of further study.[
