Efficacy of a new microbubble contrast agent of C_3F_8 in opacification of left ventricle
- VernacularTitle:国产八氟丙烷微泡造影剂左心室超声显像效果研究
- Author:
Yinguang SUN
;
Mingqiang ZHUANG
;
Zhongwei SHI
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Contrast media;
Heart ventricle;
Swine
- From:
Chinese Journal of Ultrasonography
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of a new micro-bubble contrast agent of C_3F_8 in the opacification of the left ventricle. Methods Seven pigs received a bolus injection of C_3F_8 (0.002) and (0.02) (ml/kg) intravenously. Left ventricular opacification grades and number of endocardial border delineation segments were observed and left ventricular ejection fraction(LVEF) were measured using modified Simpson method after each intravenous contrast injection. Heart rate and respiration rate were recorded before and after each injection. Results There was a significant improvement for every measurement of contrast enhancement in each intravenous injection. In addition, part of myocardial tissue could be enhanced after contrast injection. There was no difference in heart rate and respiration rate between pre- and post-injection. Conclusions This new contrast agent is safe and helpful in delineating endocardial border of the left ventricle.
