Poor prognosis associated with vascular endothelial growth factor(VEGF) and platelet drived endothelial cell growth factor(PD-ECGF) expression in aged patients with gastric carcinoma
- VernacularTitle:血管内皮生长因子与血小板衍化内皮细胞生长因子在老年人胃癌组织中的表达
- Author:
Fuxin LUAN
;
Mengwei WANG
;
Guo YU
;
Yali LV
;
Mei ZHONG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Endothelial growth factors;
Platelet-drived growth factor
- From:
Chinese Journal of Geriatrics
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of vascular endothelial growth factor (VEGF) and platelet drived endothelial cell growth factor (PD-ECGF) and their influence on the clinicopathological characteristics and the prognosis in aged patients with gastric carcinoma. Methods The expression of VEGF and PD-ECGF were examined with immnunohistochemical technique through preoperative biopsied specimens in 92 cases. Results The expression of VEGF and PD-ECGF were significantly higher in gastric carinoma than in chronic atrophic gastritis. VEGF and PD-ECGF levels in advanced carcinoma were higher compared with early carcinoma( P
