Regulation of tumor suppressor gene methylation in human gastric cancer
- VernacularTitle:抑癌基因甲基化与胃癌研究进展
- Author:
Qi LIN
;
Shifu ZHOU
- Publication Type:Journal Article
- Keywords:
gastric neoplasm;
tumor suppressor gene;
DNA methylation
- From:
China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
DNA methylation is one of the regulators on the expression of genes,and the expression of genes can be ”silenced” by hypermethylation of the tumor suppressor genes,which is in close relationship with carcinogenesis.Gastric cancer is caused by multiple factors and multiple genes alteration and prolonged interaction.among them ,There is considerable relation between the hypermethylation of the tumor suppressor genes and the gastric carcinogenesis.
