Study on feasibility and influence factors of ultrasound guided thrombin injection for treatment of iatrogenic pseudoaneurysms
- VernacularTitle:超声引导凝血酶注射治疗股动脉假性动脉瘤可行性及影响因素探讨
- Author:
Lan HUANG
;
Jun JIN
;
Jun QIN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Aneurysm,false;
Thrombin
- From:
Chinese Journal of Ultrasonography
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility and influence factors of ultrasound guided thrombin injection(UGTI) for the treatment of iatrogenic femoral pseudoaneurysms(PA). Methods Fifteen iatrogenic PA patients following femoral arterial puncture for coronary arterial angiography and PCI were treated with UGTI. One coronary arterial angiography and 14 PCI were performed in 5 males and 10 females. Nine simple PA with one lobe and 6 complex PA with two or three lobes. PA form,size,neck length and width,thrombin dose, therapic effect and complications were analysed. Duplex sonographic follow-up examination was performed at 24 hours and 5-7 days. Results Mean volume of PA was (13?5)cm 3. Twenty-one thrombin injections were performed. Mean thrombin dose was (250?120) IU in simple and (650?150) IU in complex PA. Primary success rate was 100% for 9 simple and 66.7 % for 4 of 6 complex PA. Recurrence occurred in one complex PA after 24 hours of UGTI and another complex PA reappear was detected after 15 days of UGTI, PA were completely obliterated after 3 times thrombin injections. Secondary success rate was 100%. No thromboembolic,infectious,allergic complications occurred. Conclusions UGTI is safe and effective as first-line therapy of iatrogenic pseudoaneurysms following femoral arterial puncture for PCI. Geometry form of PA is determinant factor of primary success rate.
