Clinical characters and treatments of children and adolescent spinal bone tumors
- VernacularTitle:儿童及青少年脊柱肿瘤
- Author:
Jianru XIAO
;
Haifeng WEI
;
Huajiang CHEN
- Publication Type:Journal Article
- Keywords:
Child;
Adolescence;
Spine;
Bone neoplansms
- From:
Chinese Journal of Orthopaedics
1999;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical features, treatment strategy and prognosis of children and adolescent with spinal bone tumors. Methods Forty-three patients were retrospectively investigated from January 1987 to June 2002, thirty-one of which were male, and the others were female. The age of patients ranged from 3 to 16 years with an average of 11.8 years. The pathological examination suggested that tumor-like conditions were 11 cases (25.6%), benign tumors 13 cases (30.2%), and malignant tumors 19 cases (44.2%). The cervical vertebrae tumors were 15 cases, thoracic vertebrae 16 cases, lumbar vertebrae 6 cases, and sacral vertebrae 6 cases. Treatment included: 1 case of malignant lymphoma was only subjected to chemotherapy; and the others were undertaken tumor resection and bone grafting to fusion with or without internal fixation. All patients of malignant tumors were performed adjuvant radiotherapy or chemotherapy after operation. Results The follow-up period was from 1 to 10 years with an average of 4.3 years. All patients of benign tumors obtained satisfied outcomes with local symptom and neural deficits improved, and no tumor recurrence happened. 6 cases (2 cases of primitive neural ectodermal tumor, 1 case of Ewing's sarcoma, 1 case of neuroblastoma, 1 case of plasma cell sarcoma and 1 case of chondrosarcoma) of malignant patients were died from metastasis and systemic failure, and the ratio was 14% and 31.6% of total and malignant tumor respectively. One case of bone giant cell tumor and 1 case of Schwannoma got recurrence at 2.5 years and 10 months after operation respectively. Conclusion For patients of children and adolescent with spinal bone tumors, the prognosis of the benign is better if tumors were removed radically. However, the patients with malignant tumors had worse prognosis with higher recurrent or death rate, and its prognosis is closely correlated to tumor's characters, operation strategy, and extending postoperative therapy.
